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Kidney Diseases

Today, there are approximately 250,000 dialysis patients in Japan, and the number is growing each year. Although the various treatments for kidney diseases have improved over time, kidney failure appears to be on a rise along with advancements in general medicine. A representative example is diabetic nephropathy. In the past, diabetics were often exposed to a life or death situation due to diabetic coma or infectious disease, but this is no longer major case today because of advancements in the treatment of diabetes. It is still extremely difficult, however, to always keep diabetes under control with the help of a proper dietary regimen or insulin treatment, and radical treatments such as pancreatic transplantation and implantation of an artificial pancreas are not widely available. For these reasons, some patients develop complications after 10 to 20 years of having diabetes, which eventually leads to kidney failure.
The same can be said for other diseases. We can now treat diseases that were considered incurable in the past; however, as a result, dialysis due to kidney failure may be inevitable in some people.
The fact that Japan has become an aging society is another factor. In fact, even in healthy individuals, kidney function declines with age. The kidneys of individuals in their 70s and 80s are not fully functional even in the absence of apparent kidney disease, and they can easily go into kidney failure under a stressful condition like infection.
Widespread use of drugs also contributes the increased incidence of kidney failure. Although antiphlogistic analgesics and antibiotics are helpful in treating pain disorders and infectious diseases, they are behind the rising incidence of drug-induced renal failure.
For all of these reasons, it has become increasingly important for people to take a kidney function test and receive appropriate treatment, if necessary. We strive to accurately diagnosis each individual’s disease state and provide appropriate treatment.

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Hypertension

It has been reported that approximately 30,000,000 individuals suffer from hypertension in Japan, and in some the disease progresses without symptoms and often remains untreated. Approximately 90–95% of hypertension cases are primary, or essential, hypertension with no apparent cause. A multifactorial theory, in which excessive intake of salt, obesity, and emotional and social stress, in addition to genetic predisposition, are thought be the major contributing factors, has been proposed for the disease. Blood pressure is easily influenced by, for example, environmental factors, daily activity, and sleep. In this so-called “white coat hypertension” in which some people’s blood pressure increases in clinic even though their blood pressure at home is within the normal range, we refer to their blood pressure at home or their 24-hour blood pressure level before providing antihypertensive treatment.
The other 5–10% of hypertension cases are caused by kidney diseases, renal artery stenosis, adrenal tumor, and endocrine disorders, and such cases are referred to as secondary hypertension. Because the causes are clear, the disease can be treated radically, and from a specialized standpoint, our facility provides aggressive diagnosis and treatment for the disease.

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Endocrine and Metabolic Disorders

The human body contains endocrine organs (e.g. the pituitary, thyroid, parathyroid, and adrenal glands) that produce hormones and the gonads (e.g., the testis and ovary) that produce male and female hormones. An extremely high or low level of these hormones can cause various abnormalities in our body, including changes in appearance, hypertension, diabetes, arrhythmia, and infertility.
Our department is appointed as a Japan Endocrine Society Certified Educational Institution (with five specialized physicians and five supervisory physicians) and as a Japan Thyroid Association Certified Specialist Facility (with three specialists). Our physicians with specialized knowledge and extensive clinical experience treat patients with endocrinologic and metabolic disorders, fulfilling our responsibilities as a core hospital in the Tohoku region.

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