東北大学病院 腎臓・高血圧内科





  1. Ogihara T, Saruta T, Rakugi H, Saito I, Shimamoto K, Matsuoka H, Teramukai S, Higaki J, Ito S, Shimada K: Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial. Hypertens Res 38(1):89-96, 2015
  2. Satoh F, Morimoto R, Ono Y, Iwakura Y, Omata K, Kudo M, Takase K, Seiji K, Sasamoto H, Honma S, Okuyama M, Yamashita K, Gomez-Sanchez CE, Rainey WE, Arai Y, Sasano H, Nakamura Y, Ito S: Measurement of peripheral plasma 18-oxocortisol can discriminate unilateral adenoma from bilateral diseases in patients with primary aldosteronism. Hypertension 65(5):1096-1102, 2015
  3. Takeuchi Y, Mishima E, Shima H, Akiyama Y, Suzuki C, Suzuki T, Kobayashi T, Suzuki Y, Nakayama T, Takeshima Y, Vazquez N, Ito S, Gamba G, Abe T: Exonic Mutations in the SLC12A3 Gene Cause Exon Skipping and Premature Termination in Gitelman Syndrome. J Am Soc Nephrol 26(2):271-279, 2015
  4. Fujihara M, Yokoi Y, Abe T, Soga Y, Yamashita T, Miyashita Y, Nakamura M, Yokoi H, Ito S: Clinical Outcomes of Renal Artery Stenting for Hypertension and Chronic Kidney Disease over 12 Months in J-RAS study; A Prospective, Single-Arm, Multi-center Clinical Study. Circulation J 79(2): 351-359 , 2015
  5. Narumi K, Hirose T, Sato E, Mori T, Kisu K, Ishikawa M, Totsune K, Ishii T, Ichihara A, Nguyen G, Sato H, Ito S: Functional (pro)renin receptor is expressed in human lymphocytes and monocytes. Am J Physiol Renal Physiol 308(5):F487-499, 2015
  6. Kunikata H, Aizawa N, Kudo M, Mugikura S, Nitta F, Morimoto R, Iwakura Y, Ono Y, Satoh F, Takahashi H, Ito S, Takahashi S, Nakazawa T: Relationship of Ocular Microcirculation, measured by Laser Speckle Flowgraphy, and Silent Brain Infarction in Primary Aldosteronism. PLOS ONE 10(2):e0117452, 2015
  7. Ito S: In Vitro Study of the Juxtaglomerular Apparatus and Its Implications in the Chronic Kidney Disease (Arthur C. Corcoran Memorial Lecture). Hypertension 65; 970-975, 2015
  8. Senda M, Ogawa S, Nako K, Okamura M, Sakamoto T, Ito S: The strong relation between post-hemodialysis blood methylglyoxal levels and post-hemodialysis blood glucose concentration rise. Clin Exp Nephrol 19(3); 527-533, 2015
  9. Ogawa S, Takiguchi J, Nako K, Okamura M, Sakamoto T, Kabayama S, Mori T, Kinouchi Y, Ito S: Elucidation of the etiology and characteristics of pink urine in young healthy subjects. Clin Exp Nephrol. 19(5); 822-829, 2015
  10. Ogawa S, Nako K, Okamura M, Sakamoto T, Ito S: Stabilization of postprandial blood glucose fluctuations by addition of GLP-analog administration to intensive insulin therapy. J Diabetes Invest6(4); 436-442,2015
  11. Yamamoto T, Nakayama M, Miyazaki M, Matsushima M, Sato T, Taguma Y, Sato H, Ito S: Relationship between low blood pressure and renal/cardiovascular outcomes in Japanese patients with chronic kidney disease under nephrologist care: the Gonryo study. Clin Exp Nephrol. 19(5); 878-886, 2015
  12. Konosu-Fukaya S, Nakamura Y, Satoh F, Felizola SJ, Maekawa T, Ono Y, Morimoto R, Ise K, Takeda K, Katsu K, Fujishima F, Kasajima A, Watanabe M, Arai Y, Gomez-Sanchez EP, Gomez-Sanchez CE, Doi M, Okamura H, Sasano H: 3β-hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma. Mol Cell Endocrinol 408:205-212, 2015
  13. Felizola SJ, Katsu K, Ise K, Nakamura Y, Arai Y, Satoh F, Sasano H: Pre-B Lymphocyte Protein 3 (VPREB3) Expression in the Adrenal Cortex: Precedent for non-Immunological Roles in Normal and Neoplastic Human Tissues. Endocr Pathol. 26(2):119-128, 2015
  14. Mishima E, Hashimoto J, Akiyama Y, Seiji K, Takase K, Abe T, Ito S: Posterior reversible encephalopathy syndrome treated with renin-angiotensin system blockade. J Neurol Sci 355(1-2):219-221, 2015
  15. Hashimoto J, Ito S: Aortic Blood Flow Reversal Determines Renal Function: Potential Explanation for Renal Dysfunction Caused by Aortic Stiffening in Hypertension. Hypertension 66(1):61-67, 2015
  16. Mishima E, Fukuda S, Shima H, Hirayama A, Akiyama Y, Takeuchi Y, Fukuda NN, Suzuki T, Suzuki C, Yuri A, Kikuchi K, Tomioka Y, Ito S, Soga T, Abe T: Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD. J Am Soc Nephrol 26(8):1787-1794, 2015
  17. Haneda M, Utsunomiya K, Koya D, Babazono T, Moriya T, Makino H, Kimura K, Suzuki Y, Wada T, Ogawa S, Inaba M, Kanno Y, Shigematsu T, Masakane I, Tsuchiya K, Honda K, Ichikawa K, Shide K: A new classification of Diabetic Nephropathy 2014: a report from Joint Committee on Diabetic Nephropathy. Clin Exp Nephrol 19(1):1-5, 2015
  18. Iwamori S, Sato E, Saigusa D, Yoshinari K, Ito S, Sato H, Takahashi N: A Novel and Sensitive Assay for Heme Oxygenase Activity. Am J Physiol Renal Physiol. 209(7); F667-671, 2015
  19. Satoh F, Morimoto R, Seiji K, Satani N, Ota H, Iwakura Y, Ono Y, Kudo M, Nezu M, Omata K, Tezuka Y, Kawasaki Y, Ishidoya S, Arai Y, Takase K, Nakamura Y, McNamara K, Sasano H, Ito S: Is there a role for segmental adrenal venous sampling and adrenal sparing surgery in patients with primary aldosteronism? Eur J Endocrinol. 173(4); 465-477, 2015
  20. Nakamura Y, Yamazaki Y, Konosu-Fukaya S, Ise K, Satoh F, Sasano H: Aldosterone biosynthesis in the human adrenal cortex and associated disorders. J Steroid Biochem Mol Biol. 153: 57-62, 2015
  21. Sato M, Morimoto R, Seiji K, Iwakura Y, Ono Y, Kudo M, Satoh F, Ito S, Ishibashi T, Takase K: Cost-Effectiveness Analysis of the Diagnosis and Treatment of Primary Aldosteronism in Japan; Horm Metab Res 47(11); 826-832, 2015
  22. Rong R, Ito O, Mori N, Muroya Y, Tamura Y, Mori T, Ito S, Takahashi K, Totsune K, Kohzuki M: Expression of (pro)renin receptor and its upregulation by high salt intake in the rat nephron. Peptides 63:156-162, 2015
  23. Ito S, Satoh M, Tamaki Y, Gotou H, Charney A, Okino N, Akahori M, Zhang J: Safety and efficacy of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Japanese patients with hypertension and renal dysfunction. Hypertens Res 38(4):269-275, 2015
  24. Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, Ito S, Tomioka Y, Abe T: Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides. PLoS One 25;10(11):e0143756, 2015
  25. Nakamura Y, Yamazaki Y, Felizola SJ, Ise K, Morimoto R, Satoh F, Arai Y, Sasano H: Adrenocortical carcinoma: review of the pathologic features, production of adrenal steroids, and molecular pathogenesis. Endocrinol Metab Clin North Am. 44(2); 399-410, 2015
  26. Saruta T, Ogihara T, Saito I, Rakugi H, Shimamoto K, Matsuoka H, Teramukai S, Higaki J, Ito S, Shimada K: Comparison of olmesartan combined with a calcium channel blocker or a diuretic in elderly hypertensive patients (COLM Study): safety and tolerability. Hypertens Res 38(2): 132-136, 2015
  27. Oba I, Mori T, Chida M, Kurasawa N, Naganuma E, Sato E, Koizumi K, Sato S, Tsuchikawa M, Ito S: Glucose and Insulin Response to Peritoneal Dialysis Fluid in Diabetic and Nondiabetic Peritoneal Dialysis Patients. Adv Perit Dial 31: 11-16, 2015
  28. Ogawa S, Nako K, Okamura M, Ito S: Lower urinary pH is useful for predicting renovascular disorder onset in patients with diabetes. BMJ Open Diabetes Res Care 3(1):e000097, 2015
  29. Endo S, Mishima E, Takeuchi Y, Ohi T, Ishida M, Yanai M, Kiyomoto H, Nagasawa T, Ito S: Periodontitis-associated septic pulmonary embolism caused by Actinomyces species identified by anaerobic culture of bronchoalveolar lavage fluid: a case report. BMC Infect Dis 15:552, 2015
  30. Saito-Hakoda A, Uruno A, Yokoyama A, Shimizu K, Parvin R, Kudo M, Saito-Ito T, Sato I, Kogure N, Suzuki D, Shimada H, Yoshikawa T, Fujiwara I, Kagechika H, Iwasaki Y, Kure S, Ito S, Sugawara A: Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression. PLoS One 10(12):e0141960, 2015
  31. Kurasawa N, Mori T, Naganuma E, Sato E, Koizumi K, Sato S, Oba I, Tsuchikawa M, Ito S: Association Between Home Blood Pressure and Body Composition by Bioimpedance Monitoring in Patients Undergoing Peritoneal Dialysis. Adv Perit Dial 31:38-44, 2015
  32. Kadakia KC, Tomlins SA, Sanghvi SK, Cani AK, Omata K, Hovelson DH, Liu CJ, Cooney KA. Comprehensive serial molecular profiling of an "N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment. J Hematol Oncol. 8(1):109, 2015
  33. Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T: Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases. Tohoku J Exp Med 236(3):225-232, 2015


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  6. 藤倉恵美、大内雄太、宮崎真理子、伊藤貞嘉:患者本人が決断した維持血液透析の見合わせについて、「維持血液透析の開始と継続に関する意思決定プロセスについての提言」を運用するうえでの課題;透析会誌48(12);705-712, 2015


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