東北大学病院 腎臓・高血圧内科





  1. Iwakura Y, Ito S, Morimoto R, Kudo M, Ono Y, Nezu M, Takase K, Seiji K, Ishidoya S, Arai Y, Funamizu Y, Miki T, Nakamura Y, Sasano H, Satoh F: Renal Resistive Index Predicts Postoperative Blood Pressure Outcome in Primary Aldosteronism. Hypertension 67(3):654-60, 2016.
  2. Harms PW, Hovelson DH, Cani AK, Omata K, Haller MJ, Wang ML, Arps D, Patel RM, Fullen DR, Wang M, Siddiqui J, Andea A, Tomlins SA: Porocarcinomas harbor recurrent HRAS-activating mutations and tumor suppressor inactivating mutations. Hum Pathol 51:25-31, 2016
  3. Monticone S, Satoh F, Dietz AS, Goupil R, Lang K, Pizzolo F, Gordon RD, Morimoto R, Reincke M, Stowasser M, Mulatero P: Clinical Management and Outcomes of Adrenal Hemorrhage Following Adrenal Vein Sampling in Primary Aldosteronism. Hypertension. 67(1): 146-152, 2016
  4. Nakamura Y, Kitada M, Satoh F, Maekawa T, Morimoto R, Yamazaki Y, Ise K, Gomez-Sanchez CE, Ito S, Arai Y, Dezawa M, Sasano H: Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17. Mol Cell Endocrinol. 422; 57-63, 2016
  5. Liao CW, Lin LY, Hung CS, Lin YT, Chang YY, Wang SM, Wu VC, Wu KD, Ho YL, Satoh F, Lin YH: Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients. Sci Rep.6:20862, 2016
  6. Souma T, Nezu M, Nakano D, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K,Fong GH, Nishiyama A, Ito S, Miyata T, Yamamoto M, Suzuki N: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling. J Am Soc Nephrol. 27(2); 428-438, 2016
  7. Ota H, Seiji K, Kawabata M, Satani N, Omata K, Ono Y, Iwakura Y, Morimoto R, Matsuura T, Kudo M, Tominaga J, Satoh F, Ito S, Takase K: Dynamic multidetector CT and non-contrast-enhanced MR for right adrenal vein imaging: comparison with catheter venography in adrenal venous sampling. Eur Radiol. 26(3); 622-630, 2016
  8. Satani N, Ota H, Seiji K, Morimoto R, Kudo M, Iwakura Y, Ono Y, Nezu M, Omata K, Ito S, Satoh F, Takase K: Intra-adrenal Aldosterone Secretion: Segmental Adrenal Venous Sampling for Localization. Radiology. 271(1); 265-274, 2016
  9. Imai E, Ito S, Haneda M, Harada A, Kobayashi F, Yamasaki T, Makino H, Chan JC: Effects of blood pressure on renal and cardiovascular outcomes in Asian patients with type 2 diabetes and overt nephropathy: a post hoc analysis (ORIENT-blood pressure). Nephrol Dial Transplant. 31(3); 447-454, 2016
  10. Morimoto R, Satani N, Iwakura Y, Ono Y, Kudo M, Nezu M, Omata K, Tezuka Y, Seiji K, Ota H, Kawasaki Y, Ishidoya S, Nakamura Y, Arai Y, Takase K, Sasano H, Ito S, Satoh F: A case of bilateral aldosterone-producing adenomas differentiated by segmental adrenal venous sampling for bilateral adrenal sparing surgery. J Hum Hypertens. 30(6); 379-385, 2016
  11. Mishima E, Hashimoto J, Akiyama Y, Shima H, Seiji K, Takase K, Abe T, Ito S: Impact of Small Renal Ischema in Hypertension Developmemt: Renovascular Hypertension Caused by Small Branch Artery Stenosis(Case Report); J Clin Hypertens. 18(3); 248-249, 2016
  12. Mishima E, Kikuchi K, Ota H, Akiyama Y, Suzuki T, Seiji K, Hashimoto J, Takase K, Abe T, Ito S: Detection of Segmental Renal Ischemia by Diffusion-Weighted Magnetic Resonance Imaging: Clinical Utility for Diagnosis of Renovascular Hypertension. J Clin Hypertens (Greenwich).18(4); 364-365, 2016
  13. Sato E, Mori T, Satoh M, Fujiwara M, Nakamichi Y, Oba I, Ogawa S, Kinouchi Y, Sato H, Ito S, Hida W: Urinary angiotensinogen excretion is associated with blood pressure in obese young adults. Clin Exp Hypertens 38(2): 203-208, 2016
  14. Tangri N, Grams ME, Levey AS, Coresh J, Appel LJ, Astor BC, Chodick G, Collins AJ, Djurdjev O, Elley CR, Evans M, Garg AX, Hallan SI, Inker LA, Ito S, Jee SH, Kovesdy CP, Kronenberg F, Heerspink HJ, Marks A, Nadkarni GN, Navaneethan SD, Nelson RG, Titze S, Sarnak MJ, Stengel B, Woodward M, Iseki K; CKD Prognosis Consortium: Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis. JAMA 315(2): 164-174, 2016
  15. Yamagata K, Makino H, Iseki K, Ito S, Kimura K, Kusano E, Shibata T, Tomita K, Narita I, Nishino T, Fujigaki Y, Mitarai T, Watanabe T, Wada T, Nakamura T, Matsuo S; Study Group for Frontier of Renal Outcome Modifications in Japan (FROM-J): Effect of Behavior Modification on Outcome in Early- to Moderate-Stage Chronic Kidney Disease: A Cluster-Randomized Trial. PLoS One 11(3): e0151422, 2016
  16. Yamazaki Y, Nakamura Y, Shibahara Y, Konosu-Fukaya S, Sato N, Kubota F, Oki Y,Baba S, Midorikawa S, Morimoto R, Satoh F, Sasano H: Comparison of the methods for measuring the Ki-67 labeling index in adrenocortical carcinoma: manual versus digital image analysis. Hum Pathol 53:41-50, 2016
  17. Kubota F, Nakamura Y, Konosu-Fukaya S, Azmahani A, Ise K, Yamazaki Y, Kitawaki Y, Felizola SJ, Ono Y, Omata K, Morimoto R, Iwama N, Satoh F, Sasano H: Expression of steroidogenic enzymes and their transcription factors in cortisol-producing adrenocortical adenomas: immunohistochemical analysis and quantitative RT-PCR studies. Hum Pathol. 2016 Apr 13. pii: S0046-8177(16)30035-1. doi: 10.1016/j.humpath.2016.03.016. [Epub ahead of print]
  18. Suzuki T, Yamaguchi H, Kikusato M, Hashizume O, Nagatoishi S, Matsuo A, Sato T, Kudo T, Matsuhashi T, Murayama K, Ohba Y, Watanabe S, Kanno SI, Minaki D, Saigusa D, Shinbo H, Mori N, Yuri A, Yokoro M, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Kikuchi K, Toyohara T, Suzuki C, Ichimura T, Anzai JI, Kohzuki M, Mano N, Kure S, Yanagisawa T, Tomioka Y, Tohyomizu M, Tsumoto K, Nakada K, Bonventre JV, Ito S, Osaka H, Hayashi KI, Abe T: Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. J Am Soc Nephrol; 27(7):1925-1932, 2016
  19. Nanba K, Chen AX, Omata K, Vinco M, Giordano TJ, Else T, Hammer GD, Tomlins SA, Rainey WE. Molecular Heterogeneity in Aldosterone-Producing Adenomas. J Clin Endocrinol Metab.101(3):999-1007, 2016
  20. Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD. Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation. Mod Pathol. 29(3):240-248, 2016
  21. Nanba K, Omata K, Tomlins SA, Giordano TJ, Hammer G, Rainey WE, Else T. Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations. Eur J Endocrinol. 175(2): K1-6, 2016
  22. Yamamoto T, Miyazaki M, Nakayama M, Yamada G, Matsushima M, Sato M, Sato T, Taguma Y, Sato H, Ito S: Impact of hemoglobin levels on renal and non-renal clinical outcomes differs by chronic kidney disease stages: the Gonryo study. Clin Exp Nephrol. 20(4):595-602, 2016
  23. Murakami K, Nakamura Y, Felizola SJ, Morimoto R, Satoh F, Takanami K, Katakami H, Hirota S, Takeda Y, Meguro-Horike M, Horike SI, Unno M, Sasano H: Pancreatic solitary fibrous tumor causing ectopic adrenocorticotropic hormone syndrome; Mol Cell Endocrinol 436: 268-273, 2016
  24. Nakayama M, Kabayama S, Ito S: The hydrogen molecule as antioxidant therapy: clinical application in hemodialysis and perspectives; Renal Replacement Therapy 2; 23, 2016
  25. Mishima E, Nishimiya K, Fujiwara Y, Nishizawa M, Kiyomoto H, Ito S: Serious Hypocalcemia After Withdrawal of Vitamin D Analog in Bedridden Nonagenarians with Previous Thyroidectomy: A Report of Two Cases; J Am Geriatr Soc 64(6):1374-1376, 2016
  26. Ogawa S, Takiguchi J, Shimizu M, Nako K, Okamura M, Kinouchi Y, Ito S: The Reduction in Urinary Glutamate Excretion Is Responsible for Lowering Urinary pH in Pink Urine Syndrome; Tohoku J Exp Med 239(2):103-110, 2016
  27. Fushima T, Sekimoto A, Minato T, Ito T, Oe Y, Kisu K, Sato E, Funamoto K, Hayase T, Kimura Y, Ito S, Sato H, Takahashi N: Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice; PLoS One 11(5):e0155426, 2016
  28. Oe Y, Hayashi S, Fushima T, Sato E, Kisu K, Sato H, Ito S, Takahashi N: Coagulation Factor Xa and Protease-Activated Receptor 2 as Novel Therapeutic Targets for Diabetic Nephropathy; Arterioscler Thromb Vasc Biol. 36(8):1525-33, 2016
  29. Nishikawa T, Omura M, Kawaguchi M, Takatsu A, Satoh F, Ito S, Kurihara I, Itoh H, Yanase T, Shibata H, Oki Y, Naruse M, Sakurai K, Sasamoto H, Kuwa K: Calibration and evaluation of routine methods by serum certified reference material for aldosterone measurement in blood; Endocr J. 63(12); 1065-1080, 2016
  30. Sato E, Mori T, Mishima E, Suzuki A, Sugawara S, Kurasawa N, Saigusa D, Miura D, Morikawa-Ichinose T, Saito R, Oba-Yabana I, Oe Y, Kisu K, Naganuma E, Koizumi K, Mokudai T, Niwano Y, Kudo T, Suzuki C, Takahashi N, Sato H, Abe T, Niwa T, Ito S: Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease. Scientific Reports 6: 36618, 2016
  31. Nakamura Y, Yamazaki Y, Tezuka Y, Satoh F, Sasano H: Expression of CYP11B2 in Aldosterone-Producing Adrenocortical Adenoma: Regulatory Mechanisms and Clinical Significance. Tohoku J Exp Med 240(3):183-190, 2016
  32. Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, Maeda N, Karumanchi SA, Smithies O, Takahashi N: Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proc Natl Acad Sci U S A. 113(47):13450-13455, 2016
  33. Torigoe A, Sato E, Mori T, Ieiri N, Takahashi C, Ishida Y, Hotta O, Ito S: Comparisons of amino acids, body constituents and antioxidative response between long-time HD and normal HD. Hemodial Int 20 Suppl 1:S17-S24, 2016
  34. Kuriyama S, Yaegashi N, Nagami F, Arai T, Kawaguchi Y, Osumi N, Sakaida M, Suzuki Y, Nakayama K, Hashizume H, Tamiya G, Kawame H, Suzuki K, Hozawa A, Nakaya N, Kikuya M, Metoki H, Tsuji I, Fuse N, Kiyomoto H, Sugawara J, Tsuboi A, Egawa S, Ito K, Chida K, Ishii T, Tomita H, Taki Y, Minegishi N, Ishii N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Koshiba S, Kinoshita K, Ogishima S, Takai-Igarashi T, Tominaga T, Tanabe O, Ohuchi N, Shimosegawa T, Kure S, Tanaka H, Ito S, Hitomi J, Tanno K, Nakamura M, Ogasawara K, Kobayashi S, Sakata K, Satoh M, Shimizu A, Sasaki M, Endo R, Sobue K, Tohoku Medical Megabank Project Study Group T, Yamamoto M: The Tohoku Medical Megabank Project: Design and Mission. J Epidemiol. 26(9):493-511, 2016


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